When it comes to the CBD, the main questions we often get are, “Is it marijuana?” or “How does it work?” Once we educate customers on the distinct differences between hemp and its sister plant marijuana, then come the questions on the effectiveness and which form of CBD is best. When it comes to addressing this question, there is no “cookie-cutter” answer. In this blog, let’s take a deep dive into the CBD bioavailability to share some insight to this matter.
What is CBD Bioavailability?
Bioavailability is the degree and rate at which a substance is absorbed into the bloodstream. In this case, we are referring to CBD. Bioavailability also refers to the amount of active ingredient in a compound which makes it into the bloodstream. Cannabinoids or CBD are oil based molecules in hemp extract. Since cannabinoids are oil based molecules, water solubility is a factor. Water solubility refers to a compound’s ability to dissolve into water at a specific temperature. Since our bodies are comprised of up to 60% water, the degree and rate by which CBD is absorbed in the bloodstream will vary.
CBD Bioavailability Delivery Methods
The most common methods of delivering CBD into the body are inhalation, ingestion, or topical. Based on research, each delivery method provides an approximate percentage of CBD bioavailability.
Inhalation methods consists of smoking or vaping. Smokable hemp flower in cigarette form is a basic form of smoking. Vaping is more elaborate method that requires a vaping pen and a cartridge of CBD oil. The CBD oil is heated when inhaled producing a vapor. Studies show using the inhalation method has a bioavailability between 31 – 40%.
Ingestion method consists of sublingual drops, capsules, or eatables. Sublingual delivers CBD into the bloodstream by applying drops of liquid CBD underneath the tongue. Research states this method has proven to be effective with reaching the bloodstream directly by bypassing the digestive process. According to studies, the average oral delivery yield a bioavailability range of 6 – 19%.
Topical application of CBD in lotions and creams are absorbed through the skin. Because we have endocannabinoid receptors under the skin, effects are felt locally. According to studies, topical CBD has the lowest bioavailability of all of the delivery methods. It is estimated topical CBD yield a >5% bioavailability.
Other Factors to Consider With CBD Bioavailability
When looking at CBD bioavailability, there are some factors to consider. One factor is state of health or pre-existing health conditions. Poor or impaired liver function has a notable impact on the effectiveness and time span CBD remains in the body. Another factor is fasted versus fed states. When CBD is taken with food versus on an empty stomach, CBD absorption is 3 – 5 times better. Studies have shown including health sources of dietary fat in your meal aid in dissolving CBD into smaller particles making absorption easier.
Conclusion
We hope that you have some understanding of what CBD bioavailability is, and how the delivery method plays a significant role in the percentages of CBD that enters your bloodstream. Health and food consumption are just two of a few other factors to consider with CBD bioavailability.
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